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Several other brain-related disorders besides depression are related to low serotonin, including autism, ADHD, bipolar disorder, sleep disorders, and schizophrenia (3).

Many people with depression or other serotonin deficiency symptoms and conditions are searching for better ways to increase serotonin levels naturally without the use of drugs.

Do so only if you are working with a knowledgeable health care professional. Tryptophan: Tryptophan might seem like a logical serotonin supplement to try first since tryptophan is a precursor of serotonin.

Together, they can cause too large an increase in serotonin, which can result in a potentially serious condition known as serotonin syndrome. Tryptophan is an amino acid commonly found in protein-rich foods like animal products.

Vitamin B6 (pyridoxine): Vitamin B6 must be present to facilitate conversion of either 5-HTP or tryptophan into serotonin (17, 18).

It comes from Griffonia simplicifolia, an African woody shrub. But we’ve put it in the amino acid category since it’s so closely associated with tryptophan. S., Canada, and the United Kingdom, 5-HTP is sold as an over-the-counter supplement for ADHD, anxiety, depression, fibromyalgia, migraines, sleep disorders, and weight loss (7).Three of the most widely used serotonin supplements are the amino acids tryptophan, 5-HTP, and SAM-e.Note that it is not considered safe to mix any of these amino acid supplements with antidepressant medications (4).All of the B vitamins are needed for a healthy, functioning nervous system and several are needed to synthesize serotonin (16).Here are a few that are integrally connected to serotonin production.

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